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潘文驥 助理教授 

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 Assistant Professor Wen-Chi Pan







利用流行病學方法,研究環境因子(如綠蔽度、交通工具、空氣汙染)與慢性疾病之關係。以因果中介模型(Causal Mediation Model)來探討慢性發炎在環境暴露與癌症之關聯性,並同時發展高維度統計模型,以分析中介因子及共暴露因子對於疾病的影響。



List of selected publications


1. Wen-Chi Pan, Chuh-Da Wu, Mu-Jean Chen, Yen-Tsung Huang, Chien-Jen Chen, Huey-Jen Su, and Hwai-I Yang. Fine Particle Pollution, Alanine Transaminase, and Liver Cancer: A Prospective Cohort Study in Taiwan (REVEAL-HBV). Journal of the National Cancer Institute, 108(3), DOI:10.1093/jnci/djv341, 2016.
2. Yen-Tsung Huang and Wen-Chi Pan. Hypothesis Test of Mediation Effect in Causal Mediation Model with High-dimensional Mediators. Biometrics, DOI: 10.1111/biom.12421, 2015.
3. Wen-Chi Pan, Luke D. Boyle, Elissa H. Wilker, Farzaneh A. Sorond, Brent A. Coull, Petros Koutrakis, Murray A. Mittleman, Lewis A. Lipsitz, and Gregory A. Wellenius. Ambient Temperature Alters Cerebral Hemodynamics in the Elderly. PLOS One, DOI:10.1371/journal.pone.0134034, 2015.
4. Wei Jie Seow, Wen-Chi Pan, Molly L. Kile, Tong Lin, Andrea Baccarelli, Quazi Quamruzzaman, Mahmuder Rahman, Golam Mostofa, Muhammad Rakibuz-Zaman, Muhammad Kibriya, Habibul Ahsan, Xihong Lin, and David C. Christiani. Skin Cancer Gene INPPA5 variant Increases Susceptibility of Arsenic-Associated Skin Lesions in Bangladesh, Cancer, doi: 10.1002/cncr.29291, 2015
5. Wei Jie Seow, Molly L. Kile, Andrea A. Baccarelli, Wen-Chi Pan, Hyang-Ming Byun, Golam Mostofa, Quazi Quamruzzaman, Mahmuder Rahman, Xihong Lin, and David C. Christiani. Epigenome-Wide DNA Methylation Changes With Development of Arsenic-Induced Skin Lesions in Bangladesh: A Case-Control Follow-Up Study. Environmental and Molecular Mutagenesis, 55(6), 449-56, 2014.
6. Ruoxi Hu, Wen-Chi Pan, Alexey V. Fedulov, William Jester, Matthew R. Jones, Scott T. Weiss, Teynold A. Panettieri, Jr., Kelan Tantisira, and Quan Lu. MicroRNA-10a Controls Airway Smooth Muscle Cell Proliferation via Direct Targeting of the PI3 Kinase Pathway. FASEB Journal, 28(5), 2347-57, 2014.
7. Wen-Chi Pan, Wei Jie Seow, Molly L. Kile, Elaine Hoffman, Quazi Quamruzzaman, Mahmuder Rahman, Golam Mahiuddin, Golam Mostofa, Quan Lu, and David C. Christiani. Low to Moderate Levels of Arsenic Exposure are Associated with Risk of Type 2 Diabetes in Bangladesh. American Journal of Epidemiology, 178(10), 1563-40, 2013.
8. Wen-Chi Pan, Molly L. Kile, Wei Jie Seow, Xihong Lin, Quazi Quamruzzaman, Mahumuder Rahman, Golam Mahiuddin, Golam Mostofa, Quan Lu, David C. Christiani. Genetic Susceptible Locus in NOTCH2 Interact with Arsenic in Drinking Water for Risk of Type 2 Diabetes. PLOS One, 8(8), e70792. doi:10.1371/journal.pone.0070792, 2013.
9. Wei Jie Seow, Wen-Chi Pan, Molly L. Kile, Andrea Baccarelli, Quazi Quamruzzaman , Mahmuder Rahman, Golam Mahiuddin, Golam Mostofa, Xihong Lin, and David C. Christiani. Arsenic Reduction in Drinking Water and Improvement in Skin Lesions: A Follow-Up Study in Bangladesh. Environmental Health Perspective, 120(12), 1733-8, 2012.
10. Raymond S. Oh, Wen-Chi Pan, Abdullah Yalcin, Hong Zhang, Tomás R. Guilarte5, Gökhan S. Hotamisligil, David C. Christiani, and Quan Lu. Functional RNAi Screen Identifies System A Neutral Amino Acid Transporter 2 (SNAT2) As a Mediator of Arsenic-induced Endoplasmic Reticulum Stress. Journal of Biological Chemistry, 287(8), 6025-6034, 2012.